Product Name:   Beta-Amyloid (1-42), Ultra Pure

Catalog #:       P2000022
Storage：        -20°

Molecular Mass:  4514.1 4

Peptide Purity:  >98% 

Counter Ion:     HFIP treated 

Supplied As:     No salt, as HFIP desalts the sample.  

Source:   
Recombinant. A DNA sequence encoding the human beta-amyloid  (1-42)sequence was expressed in E. coli.  
 

Sequence:   

Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala- Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala 

Resuspension:    
 Resuspend  in 1 % NH4OH, at a concentration of 1 mg/ml. Sonicate for 30 seconds to 1 minute after it has gone into solution.  

     To bring it into your buffer: After resuspension, add 5x or 10x buffer stock and water, to bring to 1x buffer. 

Description:   

Beta-amyloid peptide (Abeta), the major constituent of amyloid plaques in the brains of Alzheimer’s patients, is thought to be the cause of  Alzheimer’s Disease (AD)1-3. AD is the most common neurodegenerative disease and afflicts about 10% of the population over 60 4. The abeta,HFIP is described in Stine, et. al.3.

1) Yankner, BA, et. al., (1990) Science, 250: 279-282 

2) Selkoe, D.J., (2001) Physiol. Rev, 81: 741-766    

3) Stine, W.B. et. al., (2003) J. Biol. Chem, 278: 11612-11622

4) Frank, R.A., et. al., (2003) Neurobiology of Aging, 24: 521-536 

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β淀粉样肽(1-40),超纯,HFIPBeta-Amyloid (1-40), Ultra Pure, HFIP

β淀粉样肽(1-40),超纯,NaOHBeta-Amyloid (1-40), Ultra Pure, NaOH

β淀粉样肽(1-40),超纯,HClBeta-Amyloid (1-40), Ultra Pure, HCl

β淀粉样肽(1-42),超纯,TFABeta-Amyloid (1-42), Ultra Pure, TFA

β淀粉样肽(1-42),超纯,HFIPBeta-Amyloid (1-42), Ultra Pure, HFIP

β淀粉样肽(1-42),超纯,NaOHBeta-Amyloid (1-42), Ultra Pure, NaOH

β淀粉样肽(1-42),超纯,HClBeta-Amyloid (1-42), Ultra Pure, HCl