Ac-IETD-AFC

背景描述：
Ac-IETD-AFC是一种荧光底物，可被caspase-8和识别氨基酸序列IETD的相关酶(包括caspase-3加工酶、caspase-10和颗粒酶B1)切割，Caspase活性可通过荧光检测游离AFC(又称7-氨基-4-三氟甲基香豆素)来定量，其激发波长为400 nm，发射波长为505 nm
Ac-IETD-AFC is a fluorogenic substrate that can be cleaved by caspase-8 and related enzymes that recognize the amino acid sequence IETD, including caspase-3 processing enzyme, caspase-10, and granzyme B.1 Caspase activity can be quantified by fluorescent detection of free AFC (also known as 7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm.

序列：Ac-IETD-AFC
分子式：C31H38N5O12F3
分子量：729.66
纯度：≥95%

我司其他修饰短肽：

Ac-DEVD-CHO
Ac-IETD-CHO
Ac-YVAD-CHO
Ac-VEID-CHO
Z-VF-CHO
Z-LLF-CHO
MG-132/Z-LLL-CHO
Ac-AAVALLPAVLLALLAPIETD-CHO
E-64d, Loxistatin
Ac-Leu-Leu-Nle-CHO
Ac-Leu-Leu-Arg-CHO, Leupeptin HCl
Z-Leu-Nle-CHO, Calpeptin

Ac-DEVD-AFC
Ac-IETD-AFC
Ac-YVAD-AFC
Ac-LEHD-AFC
Ac-VEID-AFC
Ac-VDVAD-AFC
Ac-WEHD-AFC
Ac-LRSR-AFC
Suc-LLVY-AFC
Suc-AAPF-AFC
Z-Arg-Arg-AFC
Gly-Arg-AFC
Z-Leu-Arg-AFC
Z-Phe-Arg-AFC
Pro-Arg-AFC
Ala-Pro-AFC
Gly-Pro-AFC
Gly-Phe-AFC
D-Val-Leu-Lys-AFC
Ac-DEVD-AMC
Ac-IETD-AMC
Ac-YVAD-AMC
Ac-LEHD-AMC
Ac-VEID-AMC
Ac-VDVAD-AMC
Ac-WEHD-AMC
Ac-LRSR-AMC
Suc-LLVY-AMC
Z-Arg-Arg-AMC
Gly-Arg-AMC
Z-Leu-Arg-AMC
Z-Phe-Arg-AMC
Pro-Arg-AMC
Ala-Pro-AMC
Z-Gly-Gly-Arg-AMC
Suc-AAF-AMC
Ac-Orn-Phe-Arg-AMC
D-Val-Leu-Lys-AMC
Suc-AAPF-AMC
Ac-DEVD-PNA
Ac-IETD-PNA
Ac-IEPD-PNA
Ac-YVAD-PNA
Ac-LEHD-PNA
Ac-VEID-PNA
Ac-VDVAD-PNA
Ac-LEVD-PNA
MeoSuc-AAPF-PNA
Z-VGR-PNA

[Z-Arg-Arg]2-CV
[Z-DEVD]2-CV
[Z-Leu-Arg]2-CV

Z-Arg-SBzl
Z-Lys-SBzl
Z-Gly-Arg-SBzl
Z-Phe-Arg-SBzl
Boc-AAD-SBzl