小鼠抗扎伊尔埃博-拉病-毒糖蛋白（gp）IgG ELISA试剂盒
2019-07-05
产品详情
- 产地 美国
- 产品名称小鼠抗扎伊尔埃博-拉病-毒糖蛋白（gp）IgG ELISA试剂盒
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- 简介
AE-320600-1 小鼠抗埃博拉病毒糖蛋白（gp）IgG ELISA试剂盒Mouse Anti-Zaire-Ebola virus glycoprotein (GP) IgG ELISA Kit, 96 tests
背景介绍：
埃博拉病毒(EBOV)以病毒性出血热的形式在人类和非人灵长类动物中引起严重疾病。埃博拉病毒的名称取自埃博拉河和分类后缀病毒。埃博拉病毒(Zaireebolvirus)是单粒子病毒目(Mononegavirales，Mononegavirales)丝状病毒科(Filovridae)Ebolvirus属的一个病毒学分类群。该物种只有一个病毒成员，即埃博拉病毒(EBOV)。埃博拉病毒(ZEBOV)引起高致死性出血热，导致90%的患者在几天内死亡。大多数关于ZEBOV免疫应答的信息来自于体外研究和动物模型。埃博拉病毒攻击人体的每一个器官和组织，除了骨骼肌和骨骼。埃博拉被列为4级病原体(高于艾滋病)，潜伏期为2至21天(平均7至14天)。目前已知的埃博拉病毒有四种：、、莱斯顿和TAI。都会引起亚人类灵长类动物的疾病。只有埃博拉莱斯顿不会引起人类疾病。埃博拉患者的死亡率在60%至90%之间，埃博拉患者的死亡率为60%，埃博拉患者的死亡率为90%。
GSI已克隆并表达了具有较高抗原性的埃博拉病毒核蛋白(约720 aa，~82 KDA，全长)，并制备了相应的抗体。研制了抗体埃博拉病毒ELISA试剂盒，用于检测各种现有疫苗的免疫效果，并对新疫苗进行检测。
Ebola virus (EBOV) causes severe disease in humans and in nonhuman primates in the form of viral hemorrhagic fever. The name Ebola virus is derived from the Ebola River (a river that was at first thought to be in close proximity to the area in Zaire where the first recorded Ebola virus disease outbreak occurred) and the taxonomic suffix virus. Zaire ebolavirus is a virological taxon included in the genus Ebolavirus, family Filoviridae, order Mononegavirales. The species has a single virus member, Ebola virus (EBOV). Ebolavirus species Zaire (ZEBOV) causes highly lethal hemorrhagic fever, resulting in the death of 90% of patients within days. Most information on immune responses to ZEBOV comes from in vitro studies and animal models. Ebola Zaire attacks every organ and tissue in the human body except skeletal muscle and bone. Ebola is classified as a Level 4 pathogen (higher than AIDS) with a 2 to 21 day (7 to 14 days average) incubation period. There are currently four known strains of Ebola: Zaire, Sudan, Reston and Tai. All cause illness in sub-human primates. Only Ebola Reston does not cause illness in humans. The mortality rate of Ebola victims is between 60% and 90%; with Ebola Sudan at 60% and Ebola Zaire at 90%.
GSI has cloned and expressed Ebola virus nucleoprotein (~720 aa, ~82 kda, full length) that is highly antigenic and made appropriate antibodies.
Antibody ELISA kit was developed to determine the efficacy of various existing vaccines and test new vaccines. These kits help determine the
levels of Ebola virus nucleoprotein antibody during natural infection or in vaccinated individuals.
注：本试剂盒仅用于科学研究使用。
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