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beta amyloid [25-35] peptide
2019-07-31
产品详情
- 产地 美国
- 产品名称beta amyloid [25-35] peptide
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- 简介
Beta-amyloid production results from cleavage in the extracellular domain of APP by the beta-secretase (BACE1), which results in the production of the APP C-terminal fragment C99. This fragment is further cleaved by the gamma-secretase at residues 40-42 to produce beta-amyloid 40 and 42 peptides. Beta-amyloid aggregation and neuritic plaque formation are pathologic hallmarks of Alzheimer disease. This peptide corresponds to the human beta-amyloid 25-35 peptide, which induces apoptosis in cells.Human: H-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-OH or H-GSNKGAIIGLM-OH
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