ghrelin peptide
2019-07-31
产品详情
- 产地 美国
- 产品名称ghrelin peptide
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- 简介
Ghrelin (also called Ghrelin-28) is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Ghrelin induces the release of growth hormone from the pituitary gland. Ghrelin has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. The 117-aa Ghrelin precursor, the growth hormone-releasing peptide (GHRP), is cleaved into 3 chains: Ghrelin-27 (27 aa), Ghrelin-28 (28 aa) and obestatin (23 aa). Ghrelin-28 is a 28-aa peptide modified by O-octanoylation or O-decanoylation essential for activity. The O-decanoylated forms Ghrelin-27-C10 and Ghrelin-28-C10 differ in the length of the carbon backbone of the carboxylic acid bound to Ser-26. Cat. No. 350193 corresponds to the Ghrelin-28-C8 form.Human: H-Gly-Ser-Ser(octanoyl)-Phe-Leu-Ser-Pro-Glu-His-Gln-Arg-Val-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg-OH or H-GSS(octanoyl)FLSPEHQRVQQRKESKKPPAKLQPR-OH
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