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glucagon [19-29] peptide
2019-07-31
产品详情
- 产地 美国
- 产品名称glucagon [19-29] peptide
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- 简介
Glucagon [19-29] corresponds to the C-terminal fragment of glucagon, a hormone secreted in the A cells of the islets of Langherans that plays a key role in glucose metabolism and homeostasis. Glucagon [19-29] is a potent Ca2+/Mg2+-ATPase inhibitor. It inhibits secretagogue-induced insulin secretion in beta-cells (IC50<1 pM) and Ca2+/Mg2+-ATPase activity in liver plasma membranes (IC50=0.75 nM). It also contributes to the positive inotropic effect of glucagon in cardiac cells by amplifying the cytosolic Ca2+ signal.Human: H-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH or H-AQDFVQWLMNT-OH
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