mart-1 [27-35] peptide
2019-07-31
产品详情
- 产地 美国
- 产品名称mart-1 [27-35] peptide
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- 简介
MART-1 (Melanoma antigen recognized by T-cells 1) is a melanocyte differentiation antigen recognized by the cytotoxic T-lymphocytes. MART-1 is only found in melanoma, melanocyte cell lines and the retina. MART-1 is involved in melanosome biogenesis by ensuring the stability of GPR143. It plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes. MART-1 [27-35] sequence is a very common immunogenic epitope for HLA-A2-restricted melanoma-specific tumor-infiltrating lymphocytes (TIL) and may be useful for the development of immunotherapeutic strategies.Human: H-Ala-Ala-Gly-Ile-Gly-Ile-Leu-Thr-Val-OH or H-AAGIGILTV-OH
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