产品背景Description 

Melatonin receptor-1A (MTR-1A) is a high affinity receptor for melatonin, which mediates the reproductive and circadian actions of melatonin. MTR-1A activity is mediated by pertussis toxin sensitive G-proteins that inhibit adenylate cyclase activity. MTR-1A is expressed in hypophyseal pars tuberalis and hypothalamic suprachiasmatic nuclei (SCN). MTR-1A belongs to the G-protein coupled receptor 1 family.

别名Alternate Names 

Melatonin receptor type 1A; Mel1a melatonin receptor; Mel-1A-R; MTNR1A; MTR1A

应用说明Application Notes 

E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500

引用文献Product Citations 

[1] Kang NH et al. 2016. Brain Res. 1652: 89-96. PMID 27693415. [2] Wang S et al. 2012. Pain. 153(120): 2448-57. PMID 23046768. [3] Peliciari-Garcia R et al. 2011. Chronobiology International. 28(1): 21-30. PMID 21182401. [4] Ahn S et al. 2011. Auris nasus Larynx. 39(5): 479-483. PMID 22055508. [5] Corthell JT. et al. 2013. Neuroscience. PMID 24365461. [6] Huang F et al. 2013. Neural Regeneration Research. 8(32): 2991-3002.