产品背景Description
Transthyretin (TTR or prealbumin) is a major thyroid-hormone binding protein involved in transporting thyroxine from the bloodstream to the brain. Sequence variants of Transthyretin have been identified in amyloid fibrils from patients with familial amyloidotic polyneuropath (FAP), the most common form of hereditary systemic amyloidosis. Transthyretin is mostly expressed in the choroid plexus but is also found in the liver.
别名Alternate Names
Transthyretin; prealbumin; TBPA; TTR; ATTR; PALB
应用说明Application Notes
E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:200-1:500
引用文献Product Citations
[1] Zheng F et al. 2016. Sci Rep. 6: 24238. PMID 27053000. [2] Sourisseau M et al. 2013. Gastroenterology. doi: 10.1053/j.gastro.2013.07.026. PMID 23891978.