产品背景Description 

PTCH1 is a receptor for sonic hedgehog, indian hedgehog and desert hedgehog that associates with the smoothened protein to transduce the hedgehog's protein signal. Defects in PTCH1 are the cause of several structural anomalies of the brain such as the basal cell nevus syndrome and holoprosencephaly type 7.

别名Alternate Names 

Protein patched homolog 1; PTC; PTC1; PTCH1; PTCH

应用说明Application Notes 

E: 1:500-1:1,000; WB: 1:100-1:500; IF: 1:100-1:500; IHC: 1:100-1:500

引用文献Product Citations 

Gordon L. et al. 2010. Developmental Dynamics. 239(11): 2921-2932. PMID# 20931659