Sex hormone-binding globulin (SHBG) functions as an androgen transport protein and is also involved in receptor mediated processes. SHBG is a homodimer and each dimer binds one molecule of steroid. SHBG is specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. SHBG regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration.
SHBG; Sex hormone-binding globulin; Sex steroid-binding protein; SBP; Testis-specific androgen-binding protein; ABP; Testosterone-estrogen-binding globulin; Testosterone-estradiol-binding globulin; TeBG
E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
Li Y et al. 2015. Ultrastruct Pathol. 39(2): 121-30. PMID 25879298.